What it does
I'm not aware of "Infusion" as an official Magic: The Gathering keyword or ability. It's possible you're thinking of a different mechanic, or this may be a custom or unofficial term.
You might be thinking of one of these similar-sounding mechanics: Infect (deals damage as -1/-1 counters to creatures and poison counters to players), Channel (discard a card to activate an ability), or Adapt/Bolster type counter mechanics. There's also Fuse on split cards, which lets you cast both halves of a split card from your hand.
If you can confirm the exact card or set you saw "Infusion" on, I can give you an accurate breakdown of how it works and where it matters in Commander. I'd rather point you to the correct ruling than guess and give you misinformation that could cost you a game.
Iconic cards with Infusion
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