"Disintegration Ray" isn't a standard Magic keyword or named ability—it doesn't appear in the comprehensive rules or on any official card. You may be thinking of a custom card, a card from another game, or misremembering a name.
There are real cards with similar flavor, like Disintegrate (an X-spell dealing X damage that exiles a creature if it would die, preventing regeneration and death-trigger value) or various "deals damage and exiles" effects. The classic nuance with exile-on-death effects is that they bypass regeneration, indestructible-via-shields don't always help, and they deny graveyard recursion—relevant in Commander where reanimator and death-trigger decks are common.
If you can share the exact card name or text, I'll explain its rules, interactions, and Commander applications precisely.